Research

There have been numerous observational studies exploring the relationship between the concentrations of Lutein and Zeaxanthin in the macula, their dietary intake, and overall eye health. These studies suggest that dietary supplementation with Lutein and Zeaxanthin may play a role in supporting the health of the retina and maintaining normal visual functions.

Additionally, the antioxidant properties of Lutein and Zeaxanthin have been researched for their potential role in supporting eye health, particularly in the context of environmental stressors and the natural aging process of the eyes.

A study conducted by Richer et al., 2004, involving ninety participants, examined the effects of Lutein supplementation, both alone and in combination with a broad-spectrum of antioxidants, vitamins, and minerals. The study reported observations of improvements in various aspects of visual function, such as visual acuity, objective visual function parameters, photo-stress recovery, and contrast sensitivity, over a 12-month period.

In an Italian study involving 50 participants, a daily intake of a cocktail containing antioxidants and 15 mg of purified Lutein was observed. The study, conducted by Massacesi et al., 2001, reported enhancements in visual acuity over an 18-month period, highlighting the potential role of Lutein in supporting eye health.

Further research by Dagnelie et al., 2000, explored the effects of a 40 mg daily dose of Lutein over nine weeks. This study observed improvements in visual acuity, suggesting the potential of Lutein in supporting various aspects of visual function.

Additionally, a study by Bone et al., 2003, examined the impact of dietary supplements containing Lutein and Zeaxanthin on healthy volunteers. The results indicated an increase in serum concentrations of these carotenoids and an increase in the density of macular pigments, underscoring the potential role of these supplements in supporting the health of the macula and overall eye wellness.

A multicenter study involving 356 subjects, reported by Seddon et al., 1994, focused on the dietary consumption of Lutein and Zeaxanthin. The study observed a correlation between the intake of these carotenoids and eye health, particularly in relation to the macula.

In research conducted by Olmedilla et al., 2003, the role of Lutein in eye health was evaluated in 17 participants. The study noted improvements in visual acuity and glare sensitivity, along with increased serum concentrations of Lutein, suggesting its potential in supporting overall ocular wellness.

A comprehensive 20-year follow-up study (Wu et al., 2015) involving over 100,000 participants examined the relationship between carotenoid intake and eye health. The results indicated a notable association between higher intake of Lutein/Zeaxanthin and the support of macular health in both women and men.

Additionally, a 6-month, randomized, controlled clinical trial reported by Chous et al., 2015, included participants with and without diabetes. The study investigated a formula containing Lutein, Zeaxanthin, antioxidants, and botanical extracts. Results suggested improvements in visual function, macular pigment optical density (MPOD), and retinal nerve fiber layer health in subjects taking the active supplement compared to the placebo group.